Let's look at the various ways to burn ISO to USB on a Mac machine. The only thing you can't do is run an ISO file on an Apple computer. However, if you merely want to burn ISO to a USB stick, that's definitely possible. The first thing you need to know is that you can't use an ISO disk image file on a Mac, since Apple primarily uses the DMG format. This article covers three ways to burn ISO to USB stick on a Mac computer, powered by macOS Catalina, Mojave, High Serria and earier Mac OS X systems. Looking for the best ISO to USB burner for Mac? It's possible, but ISO is not native file type in Mac OS X or macOS environment, so you need to use workaround methods or employ a third-party ISO burning utility for Mac to get this done.